Conveniently located to serve the areas of San Diego, CA


Daxxify is a cosmetic injectable that reduces the appearance of wrinkles. Much like other neuromodulators, like Botox, Dysport, and Xeomin, this injectable targets hyperfunctional muscles and relaxes them. (1) Treatment is safe and extremely useful for correcting wrinkles in many areas of the face. With a few simple injections, Daxxify can reduce wrinkles in the forehead, glabellar lines, and crow’s feet for up to 6 months.

At Alexus Med Spa, our staff of medical professionals are equipped with the knowledge and skill to perform both surgical and nonsurgical cosmetic procedures. We offer a wide range of services including dermal fillers, laser skin resurfacing, and facials. Overseen by board-certified plastic surgeon Dr. John T. Alexander II, we practice safe and effective aesthetic medicine to help our patients meet their cosmetic goals.

To schedule a private Daxxify consultation, please call our San Diego office at (888) 463-9532 or fill out this online contact form to get started.

How Does Daxxify Work?

Like Botox, Daxxify is a cosmetic injectable that uses botulinum toxin (BoNT-A) to target the underlying cause of dynamic wrinkles by targeting the muscle instead of treating the surface of the skin. Daxxify works to reduce wrinkles and fine lines from the inside out.

How Does BoNT-A Smooth Wrinkles?

The brain releases a neurotransmitter called acetylcholine to contract muscles. With contraction, the skin above the muscle contracts as well, leading to wrinkles and fine lines where we move our faces the most. This is commonly apparent in between the eyebrows, “crow’s feet” next to the eyes, and horizontally along the forehead when we form expressions.

BoNT-A inhibits the release of acetylcholine from the brain, which affects muscle contraction, causing the muscle to relax, and smoothing wrinkles in the treatment area. BoNT-A contains a light chain and a heavy chain, and each has a particular job in relaxing the targeted muscles. These chains work together to find and stop the release of acetylcholine. If a patient has frown lines, lines around the eyes, or forehead creases, Daxxify can target each of these muscle groups to effectively reduce wrinkles. (2)

Benefits of Daxxify

There are many patient benefits of Daxxify as it:

  • Reduces wrinkles and fine lines
  • Prevents new lines from forming
  • Smooths facial skin
  • Requires no downtime
  • Provides long-lasting results
  • Produces natural-looking results

Daxxify can help to correct:

  • Crow’s Feet
  • Lip Lines
  • Chin Dimpling
  • Forehead Lines
  • Neck Lines
  • Sagging Eyebrows
  • TMJ (jaw tension)
  • DAO Lines (corners of mouth)
  • Nasolabial Folds (laugh lines)
  • Lip Wrinkles (pucker lines)
  • Glabellar Lines (lines between brows)
  • Bunny Lines (side of the nose)

Botox vs. Daxxify


Patients often prefer Daxxify over Botox for its quicker onset of results. Some patients also find that Daxxify’s effects last longer, reducing the frequency of their treatments.


Patients could be looking for a Botox alternative or additional wrinkle reduction after receiving other injectables. Though this treatment is minimally invasive, they should be in good overall health. Good Daxxify candidates are not allergic to anything within the injectable and are not currently pregnant or nursing. They should also have realistic expectations about what the treatment can achieve.

If you are curious about your candidacy, please schedule a consultation at Alexus Med Spa.

Personal Consultation

For your Daxxify consultation, one of our knowledgeable providers will meet with you to discuss your concerns. They will inquire about your medical history and whether or not you have ever received neuromodulators before. Next, they will examine your face to assess where to place the Daxxify injections. Your provider will explain the procedure process thoroughly and answer any questions you may have to prepare you. They will create a treatment plan that works best for you. Depending on your circumstances, they may perform the injections directly after your private consultation. If not, a member of our staff will schedule your treatment for a future date.


To ensure optimal outcomes for your Daxxify treatment, it is important to follow the preoperative instructions provided by our team. Please refrain from smoking tobacco and nicotine products and do not consume alcohol. Avoid taking aspirin, ibuprofen, or other anti-inflammatory medications that thin your blood. For the same reason, please steer clear of certain herbal supplements like vitamin E and ginger. We encourage you to wear loose-fitting clothes to remain comfortable during your appointment. It is also helpful to arrive with no makeup or other cosmetics on your face.

Daxxify Treatment Plan

The Daxxify procedure begins with a thorough cleansing of the treatment area. If requested, they may apply a small amount of topical anesthetic to numb the area before starting the procedure. Next, they carefully place each injection in the treatment area. They may ask you to smile or frown to target specific muscles and reduce wrinkles, focusing on your areas of concern. After your last injection, they may give you an ice pack to alleviate any immediate discomfort. Your provider may perform this procedure right after your consultation as it typically takes 10 to 20 minutes to complete.

Long-Lasting Results

There is no downtime associated with Daxxify injections. You may experience irritation in and around the treatment area, but this quickly subsides in a day or two. Try not to touch or massage the targeted areas for the first 3 to 7 days to avoid migration to an unintended muscle. Though most Daxxify patients go back to their daily activities quickly, please refrain from bending over and lying down for 4-6 hours. Avoid exposing the skin to UV rays by wearing sunscreen while outside.

You should expect to notice a reduction in your wrinkles and lines 2 or 4 days after your treatment. These results get more noticeable with time and can last up to 6 months without needing a touch-up. You may return to Alexus Med Spa to improve or maintain your Daxxify results. This typically means 2 visits a year to continue looking your best.

Corresponding & Complementary Treatments

Botox Cosmetic

Botox uses the same mechanics as Daxxify to temporarily relax muscles and reduce wrinkles. To achieve non-surgical anti-aging, our medical professionals expertly place Botox injections directly into overactive muscles in the face. This works to smooth the skin as well as temporarily prevent new wrinkles from forming.

Dermal Fillers

To volumize your facial features and treat wrinkles and fine lines, we offer dermal filler injections. These injectables contain substances like hyaluronic acid, calcium hydroxylapatite, and poly-L-lactic acid to correct skin imperfections and add symmetry to the face. Some fillers, like Sculptra, stimulate collagen production to improve the skin’s surface from the inside out. Juvederm is a collection of hyaluronic acid fillers that add volume and moisture to the skin to rejuvenate the targeted areas. Dermal fillers can be paired with Daxxify to further improve your results.

Chemical Peels

Alexus Med Spa offers a variety of chemical peels that resurface the skin, treat dark spots, and smooth textured skin. During this treatment, your provider applies a specially formulated acid solution to the face and swiftly removes it after the outermost layer of the skin is affected. From there, the damaged skin peels away, leaving a new unaffected layer on the surface. Peels are an optimal treatment choice whether you want to lightly remove some sun damage or reduce mild acne scars.

Cost of Daxxify in San Diego

Each patient requires a personalized treatment plan to achieve their cosmetic goals. During your private consultation, your provider will give you an accurate cost estimation according to the specifics of your treatment plan.

To take the first step with Daxxify injections, call our office at (888) 463-9532 to schedule an appointment today.


Does Daxxify provide natural results?

Daxxify often spreads very easily and covers a large surface area, making it particularly good at treating forehead wrinkles. This also helps patients achieve a natural-looking and softer result.

Will others be able to tell that I have received this treatment?

The goal of any Daxxify application is to minimize wrinkles and rejuvenate the face without negatively affecting a patient’s expression. In the hands of an experienced provider, Daxxify is undetectable to the untrained eye. This treatment simply reduces imperfections while maintaining your natural facial features.

Is there an ideal age for Daxxify treatment?

There is no specific ideal age for Daxxify treatment since each patient ages differently and has unique concerns. Generally, individuals in their 30s and older are suitable candidates for Daxxify when wrinkles caused by muscle movement become more apparent.

Are there any common side effects of Daxxify?

Most patients experience slight injection site irritation, headache, and mild discomfort. These negative effects dissipate quickly as the Daxxify settles.


  1. Gubanova E, May Haddad Tabet, Bergerova Y, et al. Assessment of Subject and Physician Satisfaction after Long-Term Treatment of Glabellar Lines with AbobotulinumtoxinA (Daxxify®/Azzalure®): Primary Results of the APPEAL Noninterventional Study. Aesthetic Plastic Surgery. 2018;42(6):1672-1680. doi:https://doi.org/10.1007/s00266-018-1200-4
  2. Field M, Splevins A, Picaut P, et al. AbobotulinumtoxinA (Daxxify®), OnabotulinumtoxinA (Botox®), and IncobotulinumtoxinA (Xeomin®) Neurotoxin Content and Potential Implications for Duration of Response in Patients. Toxins. 2018;10(12):535. doi:https://doi.org/10.3390/toxins10120535